| 龟象膏皮肤毒性实验研究 |
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| 引用本文： | 王春来,梁海英,王智慧,赵红心,谷小芳.龟象膏皮肤毒性实验研究[J].中国中医急症,2011,20(12):1966-1967,1992. |
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| 作者姓名： | 王春来 梁海英 王智慧 赵红心 谷小芳 |
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| 作者单位： | 河北省唐山市丰润区中医医院,河北唐山,064000 |
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| 摘 要： | 目的研究龟象膏对动物皮肤的毒性作用。方法利用健康SD大鼠进行完整皮肤和破损皮肤急性毒性试验;用健康白兔进行完整皮肤和破损皮肤刺激性试验;用健康豚鼠进行皮肤过敏试验。以上实验同时进行血常规检查。结果龟象膏对大鼠完整皮肤及破损皮肤均无急性毒性反应,对白兔完整皮肤和破损皮肤无刺激性,对豚鼠完整皮肤无致敏作用,血常规检查无异常现象。结论龟象膏用于治疗糖尿病肢端坏疽安全可靠。
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| 关 键 词： | 龟象膏 急性毒性 皮肤刺激性 皮肤过敏性 |
Experimental Study of Skin Toxicity of Guixiang Cream |
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| WANG Chun-lai,LIANG Hai-ying,WANG Zhi-hui,et al TCM Hospital of Fengrun District,Tangshan City,Hebei Province.Experimental Study of Skin Toxicity of Guixiang Cream[J].Journal of Emergency in Traditional Chinese Medicine,2011,20(12):1966-1967,1992. |
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| Authors: | WANG Chun-lai LIANG Hai-ying WANG Zhi-hui TCM Hospital of Fengrun District Tangshan City Hebei Province |
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| Institution: | WANG Chun-lai,LIANG Hai-ying,WANG Zhi-hui,et al TCM Hospital of Fengrun District,Tangshan City,Hebei Province(Tangshan 064000,Hebei) |
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| Abstract: | Objective：To study toxicity of Guixiang Cream on the skin of animals.Methods： A experiment of cutaneous toxicity was performed on the skin of healthy rats.Cutaneous stimulation was performed in the skin of healthy rabbit.Cutaneous hypersensitivity was performed in healthy guinea pig.Results：The Guixiang Cream had no acute toxicity,no cutaneous stimulation and no hypersensitive effects for the intact or damˉaged skin in rats,rabbits and guinnea pigs respectively.Conclusion：It is safe for Guixiang Cream to use in the clinic. |
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| Keywords: | Guixiang Cream Skin acute toxicity Skin irritation Skin hypersensitivity |
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