Fine-needle aspiration biopsy of hepatic papillary cystadenocarcinoma in Caroli's disease. |
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Authors: | X Tarroch N Tallada C Castells M Garcia |
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Institution: | Department of Pathology, Ciutat Sanitaria Universitaria Vall d'Hebron, Universitat Autònoma de Barcelona, Spain. |
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Abstract: | A case of papillary adenocarcinoma arising in Caroli's disease (CD) in a 25-yr-old woman is reported. The diagnosis of malignancy was made by ultrasound-guided, fine-needle aspiration biopsy (FNAB). As there were no metastasis, a liver transplant was performed and the diagnosis was histologically confirmed. Only 22 cases of malignant transformation of CD have been reported to date, all among middle-aged subjects (mean age: 52 yr) of both sexes. Most of these reported cases (83%) were found to be bile duct adenocarcinomas with occasional reports of hepatocellular and undifferentiated carcinomas. Our case is the youngest reported to date and the first to be diagnosed cytologically. |
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Keywords: | Cholangiocarcinoma Biliary duct tumors Liver tumors |
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