MRI对鼻咽癌颅底骨质破坏放疗前后评估的探讨

目的探讨MRI对鼻咽癌颅底骨质破坏放疗前后比较的价值。方法分析2007年9月至2008年1月49例颅底骨质破坏初诊鼻咽癌患者放疗前后MRI的变化。结果49例鼻咽癌患者放疗前均存在程度不等的颅底骨质破坏；MRI可见肿块T1WI呈中低信号，T2WI呈中高信号，骨髓高信号消失及压脂增强后明显强化。经放射治疗49例患者均呈放疗后状态。结论MRI平扫及增强扫描图像对鼻咽癌TNM分期及疗效判断有重要价值。

Assessment of skull base bone destruction by MRI in nasopharyngeal carcinoma after radiotherapy

Objective To investigate the value of MRI in evaluating the skull base bone dstrcuction in nasopharyngeal carcinoma before and after radiotherapy. Methods From September 2007 to January 2008, MR changes of 49 cases of newly diagnosed nasopharyngeal carcinoma with skull base bone destruction before and after radiation therapy were analyzed. Results Skull base bone destruction occurred in all 49 cases with nasopharyngeal carcinoma before radiation therapy; It appeared as low signal mass on T1WI and moderately high signal on T2WI. The normal high signal in the bone marrow disppeared and significantly enhanced on fat saturated T1WI after giving contrast media. After radiation therapy 49 patients presented with post radiotherapystatus. Conclusion MRI plain and enhanced scan images are of significant value in judgments the TNM staging of nasopharyngeal carcinoma.