上颌窦鳞状细胞癌眶侵犯患者眶内容物处理的探讨

目的:探讨晚期上颌窦鳞状细胞癌眶侵犯患者手术中眶内容物的处理。方法:将46例有眶侵犯的晚期上颌窦鳞状细胞癌手术患者分为眶骨壁侵犯组、眶骨膜侵犯组、眶内侵犯组,随访2、3、5年的生存率和2年复发率,并加以统计分析。结果:2、3、5年生存率和2年复发率眶骨壁侵犯组分别为65.2%、55.6%、46.7%和38.1%;眶骨膜侵犯组分别为57.1%、50.0%、45.5%和53.8%;眶内侵犯组分别为44.4%、37.5%、37.5%和62.5%。3组生存率依次降低,复发率依次升高,但均差异无统计学意义(均P>0.05)。结论:晚期眶侵犯上颌窦鳞状细胞癌患者的手术中对有眶骨壁或眶骨膜侵犯者保留眶内容物是可以考虑的。

Management in squamous cell carcinoma of maxillary sinus with orbital invasion

Objective:To explore the orbital management in advanced squamous cell carcinoma of maxillary sinus with orbital invasion.Method:Forty-six postoperative cases of advanced squamous cell carcinoma of maxillary sinus with orbital invasion were followed up. Two,three,five-year survival rates and 2-year recurrence rates were analysed in orbital bone invaded group, periorbit invaded group and orbital content invaded group.Result:Two,three,five-year survival rates and 2-year recurrence rates were 65.2%, 55.6%, 46.7% and 38.1% in orbital bone invaded group;57.1%,50.0%,45.5% and 53.8% in periorbit invaded group; 44.4%, 37.5%, 37.5% and 62.5% in orbital content invaded group,respectively. Survival rates of three groups descended and recurrence rates of three groups ascended but without statistical significance(P>0.05).Conclusion:During the surgery for advanced squamous cell carcinoma of maxillary sinus with orbital invasion without the evidence of optical nerve and eye ball involvement, preservation of orbital contents is considerable even though the orbital bone and periorbit are involved by the tumor.