干燥羊膜移植联合复合式小梁切除术治疗难治性青光眼临床观察

Objective To explore the effect and security of dry amniotic membrane transplantation com-bined with trabeculectomy on refractory glaucoma. Methods Dry amniotic membrane transplantation combined with trabeculectomy was performed on 32 cases (39 eyes) with refractory glaucoma. All the patients were followed-up for 6-24 months. The acuity of visual, filtering bleb, anterior chamber depth, IOP and the complications of operation were studied. Results The IOP was descended 59.9 % (P<0.001) from (41.3±5.1)mmHg pre-operation to(17.2±5.3) mmHg post-operation. The total success rate was 93.4 %. After operation, 34 eyes (87.2 %) were kept functional filtering bleb. 27 eyes (69.2 %) had improved visual acuity. The complications included shallow anterior chamber (5 eyes) and early postoperative hypotony (9 eyes). Conclusions Amniotie membrane transplantation combined with trabeculectomy for refractory glaucoma can effectively inhibit the sear formation, decrease the IOP and increase the success rate considerably. The method is safe and effective in the treatment of refractory glaucoma.

Clinical observation of dry amniotic membrane transplantation combined with trabeculectomy for treatment of refractory glaucoma