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| 川东獐牙菜化学成分研究 | |
| 引用本文： | 谭桂山,徐康平,徐平声,胡高云,李元建.川东獐牙菜化学成分研究[J].药学学报,2002,37(8):630-632. |
| 作者姓名： | 谭桂山 徐康平 徐平声 胡高云 李元建 |
| 作者单位： | 1. 中南大学湘雅医院药剂科,湖南,长沙,410008;中南大学湘雅医学院药学系,湖南,长沙,410078 2. 中南大学湘雅医学院药学系,湖南,长沙,410078 3. 中南大学湘雅医院药剂科,湖南,长沙,410008 |
| 基金项目： | 湖南省科技厅资助项目 (2 0 0 0 10 11-5 ) |
| 摘 要： | 目的研究川东獐牙菜(Swertia davidi Franch)活性成分。方法用硅胶色谱技术分离化学成分,用UV,IR,NMR和MS等光谱方法鉴定化合物。结果得到3个化合物,分别鉴定为:1,7-二羟基-3,8-二甲氧基酮(V);1,8-二羟基-3,7-二甲氧基酮(VI)和1,8-二羟基-3,4,7-三甲氧基酮(VII)。结论VII为新酮,其余两个酮均首次从该植物中分离得到。 |
| 关 键 词： | 川东獐牙菜 酮 川东獐牙菜素A |
| 收稿时间： | 2001-10-08 |
STUDIES ON THE CHEMICAL CONSTITUENTS OF SWERTIA DAVIDA FRANCH |
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| TAN Gui-shan,XU Kang-ping,XU Ping-sheng,HU Gao-yun,LI Yuan-jian.STUDIES ON THE CHEMICAL CONSTITUENTS OF SWERTIA DAVIDA FRANCH[J].Acta Pharmaceutica Sinica,2002,37(8):630-632. | |
| Authors: | TAN Gui-shan XU Kang-ping XU Ping-sheng HU Gao-yun LI Yuan-jian |
| Institution: | Department of Pharmacy, Xiangya Hospital, Central South University, Changsha 410008, China. |
| Abstract: | AIM To study the active constituents of Swertia davidi Franch.. METHODS Chromatography was used to isolate and purify the chemical components, their structures were identified by spectral analysis. RESULTS Three compounds were identified as 1,7 dihydroxy 3,8 dimethoxyxanthone (gentiacaulein) (V), 1,8 dihydroxy 3,7 dimethoxyxanthone (methylswertianin) (VI) and 1,8 dihydroxy 3,4,7 trimethoxyxanthone (VII). CONCLUSION Compound VII is a novel xanthone, named daviditin A, the others were isolated from Swertia davidi Franch. for the first time. |
| Keywords: | Swertia davidi Franch xanthone daviditin A |
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