Three Cases of Nodular Regenerative Hyperplasia of the Liver Following Renal Transplantation |
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| Authors: | Buffet C; Cantarovitch M; Pelletier G; Fabre M; Martin E; Charpentier B; Etienne J P; Fries D |
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| Institution: | 1Service d'Hépatogastroentérologie, Hôpital Bicêtre Le Kremlin Bicetre, France
2Service de Néphrologie, Hôpital Bicêtre Le Kremlin Bicetre, France
3Service d'Anatomopathologie, Hôpital Bicêtre Le Kremlin Bicetre, France |
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| Abstract: | We report three cases of nodular regenerative hyperplasia ofthe liver: the clinical onset of hepatic disease occurred between24 and 30 months after renal transplantation. Nodular regenerativehyperplasia was associated with peliosis hepatis in two cases,and with veno-occiusive disease in one case. Two patients developedportal hypertension, but are doing well. The third patient developedjaundice and died of septic shock. We discuss the aetiologicalrole of renal transplantation, cytomegalovirus infection, andazathioprine in the development of nodular regenerative hyperplasiaof the liver. |
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| Keywords: | Nodular regenerative hyperplasia Renal transplantation |
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