Vectorcardiographic evaluation of diabetic cardiomyopathy and of its contributing factors |
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Authors: | Erminio Vitolo Stefano Madoi Carlo Sponzilli Micaela Palvarini Donatella Silvestri Diego Castini Alberto Morabito |
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Institution: | (1) Istituto di Scienze Biomediche Sacco, Università di Milano, Milano;(2) Istituto di Statistica Medica e Biometria, Università di Milano, Milano, Italy;(3) St. Bartholomew’s Hospital, London, U.K. |
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Abstract: | Summary In order to investigate the prevalence of vectorcardiographic bites, expression of small areas of fibrosis, atrophy or degeneration
of the myocardium, we studied, using the vectorcardiograms (VCG) of 101 diabetic patients (35 with insulin-dependent and 66
with non-insulin-dependent diabetes mellitus, aged from 25 to 60 years, without hypertension, coronary artery disease, or
intraventricular conduction defects) and 228 normal control subjects, matched for age and sex. The prevalence of bites was
38.6% in diabetic patients and 10.0% in the control group (p<0.001). Diabetic patients were also subdivided into groups according
to age, sex, metabolic control, risk factors for coronary heart disease, type of diabetes, duration of diabetes and diabetic
microangiopathy. No correlation was found between any of the variables investigated nor of a combination of these, and the
presence of bites. We conclude that VCG is a sensitive test for cardiac involvement in diabetic patients but that it cannot
be used to identify any specific factor able to influence the onset and evolution of this involvement. |
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Keywords: | Cardiac involvement in diabetes mellitus Diabetic cardiomyopathy Factors influencing diabetic cardiomyopathy Vectorcardiographic bites Vectorcardiography |
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