| 血液、血制品与人类微小病毒B19的传播 |
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| 引用本文： | 耿彦生,张印法. 血液、血制品与人类微小病毒B19的传播[J]. 疾病控制杂志, 2007, 11(5): 516-519 |
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| 作者姓名： | 耿彦生 张印法 |
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| 作者单位： | 1. 河北大学医学部微生物学与免疫学教研室,河北,保定,071000
2. 河北省卫生厅卫生监督局办公室,河北,石家庄,050071 |
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| 摘 要： | 人类微小病毒B19（B19病毒）在人群中传播广泛,0.003%～0.6%的献血员带有B19病毒,在病毒血症早期献血员血液中B19DNA含量很高;血浆及血液制品中也经常能检测到B19DNA。通过输血或应用血制品能引起B19病毒的传播,B19病毒感染与多种疾病的发生有关。
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| 关 键 词： | 血液 病毒 疾病传播 |
| 文章编号： | 1008-6013（2007）05-0516-04 |
| 修稿时间： | 2007-05-06 |
Human parvovirus B19 and the safety of blood and blood-derived products |
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| GENG Yan-sheng,ZHANG Yin-fa. Human parvovirus B19 and the safety of blood and blood-derived products[J]. Chinese Journal of Disease Control and Prevention, 2007, 11(5): 516-519 |
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| Authors: | GENG Yan-sheng ZHANG Yin-fa |
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| Affiliation: | 1.Laboratory of Microbiology and Immunology,Center of Medical Science,Hebei University,Baoding 071000,China;2.Hebei Provincial Center for Health Inspection and Supervision,Shijiazhuang 050071,China |
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| Abstract: | Human parvovirus B19(B19)is a small non-enveloped DNA virus.It is widespread among populations.The prevalence of B19 viremia in blood and plasma donors has been reported to range from 0.003% to 0.6%.Extremely high viremic levels in blood are often found at an early phase of the infection in acutely infected but asymptomatic donors.As a consequence,B19 DNA has been detected at high frequency and high levels in plasma pools and their resulting plasma derivatives.Reports of transmissions attributed to plasma and plasma-derived products are numerous. |
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| Keywords: | Blood Viruses Disease transmission |
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