| 亚急性皮肤型红斑狼疮合并甲亢1例 |
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| 引用本文： | 张娟,李东霞.亚急性皮肤型红斑狼疮合并甲亢1例[J].中国皮肤性病学杂志,2013,27(1):76-77. |
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| 作者姓名： | 张娟 李东霞 |
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| 作者单位： | 内蒙古医科大学附属医院皮肤科,内蒙古呼和浩特市,010050 |
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| 摘 要： | 患者女,35岁。全身红色皮疹伴发热2个月,上半身皮疹加重20d。查体:面颈部及双上肢环状红斑,双手震颤,突眼,甲状腺肿大;ANA1∶160,SSA3(+);T4,FT4↑,TSH↓,TG-Ab,TPO-Ab↑;甲状腺彩超示:甲状腺弥漫性肿大,血流丰富。皮损组织病理示:表皮变薄,基底液化变性,真皮浅层血管及附属器周围局灶性淋巴细胞为主的炎细胞浸润,可见个别噬黑素细胞,胶原轻度嗜碱变性。诊断:SCLE合并甲亢。SCLE合并甲亢尚未见报道,可能与两者有相同的遗传及免疫学基础有关。
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| 关 键 词： | 亚急性皮肤型红斑狼疮 甲亢 自身免疫性疾病 |
A Case of Subacute Cutaneous Lupus Erythematosus Associated with Hyperthyroidism |
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| ZHANG Juan
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LI Dong-xia.A Case of Subacute Cutaneous Lupus Erythematosus Associated with Hyperthyroidism[J].The Chinese Journal of Dermatovenereology,2013,27(1):76-77. |
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| Authors: | ZHANG Juan LI Dong-xia |
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| Institution: | (Department of Dermatology, Affiliated Hospital of Inner Mongolia Medical University, Huhhot,010050, China) |
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| Abstract: | A 35-year-old female patient admitted to the hospital complaining of generalized skin rash with erythematous macules for 2 months, aggravate rashes on upper body for 20 days.Physical examination showed that erythema annulare appeared on face,neck and both upper limbs,tremor of the hands,exophthalmos,thyroid gland enlargement; ANA 1 ∶ 160; SSA 3+,thyroid function revealed that T4,FT4↑,TSH↓, TG-Ab, TPO-Ab↑;Ultrasound showed that diffuse enlargement of the thyroid and rich blood flow;Histopathology of the chest skin lesion showed that epidermal thinning,liquefaction degeneration of basal layers, in superficial layer of dermis, perivascuar and periadnexal inflammatory cells infiltration,primarily lymphocyte,visible individual melanocytes,basophilic degeneration of collagen fibers.Diagnosis:Subacute cutaneous lupus erythematosus associated with hyperthyroidism.It has not been reported, maybe they have the same genetic and immune bases. |
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| Keywords: | Subacute cutaneous lupus erythematosus Hyperthyroidism Autoimmune disease |
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