健康成年男子性激素水平调查

目的调查健康成年男子的性激素水平。方法2002年5月～2003年5月在北京、上海、西安和重庆检查20岁以上健康成年男子1080例,按年龄分为5组,进行了全面体检,并在次晨07:30～08:30肘静脉采血测定黄体生成激素(LH),卵泡刺激激素(FSH),总睾酮(TT),雌二醇(E2)和性激素结合球蛋白(SHBG),计算游离睾酮(cFT)。结果 随着年龄的老化,血清LH,FSH,E2和SHBG水平逐渐增高,cFT逐渐下降,TT无显著变化。以20-39岁值作为基础,单侧下限正常值范围cFT为0.276 nmol/L,TT为11.659 nmol/L。结论 我们的调查揭示了健康成年男子性激素随年龄老化的变化规律,提出了睾酮水平降低的参考界限值。

A survey of sex hormones in Chinese healthy male adults

Objective To investigate the blood concentrations of sex hormones in Chinese healthy male adults. Methods One thousand and eighty healthy men aged 20 to > 75 years were examined in Beijing, Shanghai, Xi'an and Chongqing from May 2002 to May 2003. After an overall physical examination, blood samples were collected from cubital vein at 07:30 to 08:30 next morning for measuring LH,FSH,TT,E2 and SHBG. The free testosterone (cFT)was calculated. Results With advancement of age, serum LH,FSH,E2 and SHBG were progressively elevated, and cFT level declined, but TT was not changed significantly. With values at age 20 to 39 years as the basis, the single lower limit of normal range of cFT was 0.276 nmol/L, and TT was 11.659 nmol/L. Conclusions The data displayed the changes of sex hormones with aging in Chinese healthy men, and raised the reference value of limit of lowering of testosterone.