Alpha2-adrenergic receptor subtype-specific activation of NF-kappaB in PC12 cells |
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Authors: | Lymperopoulos Anastasios Karkoulias Georgios Koch Walter J Flordellis Christodoulos S |
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Affiliation: | Center for Translational Medicine, Department of Medicine, Thomas Jefferson University, Philadelphia, PA 19107, USA. |
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Abstract: | |
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Keywords: | α2-ARs, α2-adrenergic receptors GPCR, G-protein coupled receptor CNS, central nervous system KO, knock-out MAPK, mitogen-activated protein kinase AP-1, activator protein-1 NF-κB, nuclear factor-kappaB PI-3K, phosphatidyl inositol-3′OH kinase ERK, extracellular signal-regulated kinase NGF, nerve growth factor PTX, pertussis toxin FBS, fetal bovine serum MEK1, MAPK/ERK kinase 1 |
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