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Alpha2-adrenergic receptor subtype-specific activation of NF-kappaB in PC12 cells
Authors:Lymperopoulos Anastasios  Karkoulias Georgios  Koch Walter J  Flordellis Christodoulos S
Affiliation:Center for Translational Medicine, Department of Medicine, Thomas Jefferson University, Philadelphia, PA 19107, USA.
Abstract:
Keywords:α2-ARs, α2-adrenergic receptors   GPCR, G-protein coupled receptor   CNS, central nervous system   KO, knock-out   MAPK, mitogen-activated protein kinase   AP-1, activator protein-1   NF-κB, nuclear factor-kappaB   PI-3K, phosphatidyl inositol-3′OH kinase   ERK, extracellular signal-regulated kinase   NGF, nerve growth factor   PTX, pertussis toxin   FBS, fetal bovine serum   MEK1, MAPK/ERK kinase 1
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