经皮电刺激对阻塞性睡眠呼吸暂停的影响

目的研究经皮颏下电刺激对睡眠期阻塞性睡眠呼吸暂停综合征的影响。方法１６例阻塞性睡眠呼吸暂停患者在接受经皮颏下电刺激（ＴＥＳ）治疗前后进行了全夜多导睡眠图监测。结果１６例中的１４例ＴＥＳ治疗成功，睡眠呼吸暂停指数（ＡＩ）下降＞５０％，平均ＡＩ下降了２９次／小时（Ｐ＜０．００１），平均呼吸暂停时间从２２秒降至７秒（Ｐ＜０．００１）呼吸暂停时间／总睡眠时间（ＴＳＴ）下降了２０％。最低血氧饱和度从７１％升至８７％（Ｐ＜０．００１）。ＴＥＳ未引起觉醒。慢波睡眠（Ⅲ＋Ⅳ）期，快动眼期（ＲＥＭ）睡眠及睡眠效率增加。结论ＴＥＳ是一种非手术的、有效的治疗阻塞性睡眠呼吸暂停综合征的方法，但对中枢性睡眠呼吸暂停无效

The effects of transcutaneous electrical stimulation during sleep on obstructive sleep apnea

OBJECTIVE: To study the effects of transcutaneous electrical stimulation during sleep on obstructive sleep apnea syndrom (OSAS). METHOD: Sixteen patients with OSAS were studied by polysomnography during all-night sleep with and without submental transcutaneous electrical stimulation (TES) of the genioglossus. RESULT: Fourteen of the 16 patients (87%) who accepted the TES were treated successfully (reduction of Al > 50%). The average apnea index showed a decrease of 29 events per hour when the TES were performed (P < 0.001). The average apnea time decreased from 22 to 7 sec (P < 0.001). The apnea time/TST decreased from 27% +/- 11% to 7% +/- 3%. The lowest SaO2 increased from 71% to 87% (P < 0.001). TES did not cause arousal. The sleep stages of SWS, and REM sleep effect (SE) increased significantly. CONCLUSION: TES is a conservative but effective treatment in patients with obstructive sleep apnea syndrome, although it failed to improve central sleep apnea.