部分脾动脉栓塞术治疗肝硬化门脉高压症46例

目的:探讨部分脾动脉栓塞术(PSE)治疗肝炎肝硬化门静脉高压症并发脾功能亢进的疗效及临床意义.方法:通过我院46例肝炎肝硬化门静脉高压症并发脾功能亢进患者行PSE,观察术前及术后血象变化、脾脏大小变化、门静脉内径变化及并发症情况.结果:与术前相比,术后白细胞及血小板计数明显上升,3 mo后稳定在一定水平,红细胞计数术前及术后无明显变化,脾脏3 mo后明显缩小,门静脉内径不同程度缩小,术后无严重并发症发生.结论:PSE治疗肝炎肝硬化门静脉高压症合并脾功能亢进安全有效.

Partial spleen artery embolotherapy for 46 patients with hepatic cirrhosis and portal hypertension

AIM: To study the curative effect and clinical significance of the partial spleen artery embolization (PSE) in the treatment of hepatic cirrhosis together with portal hypertension and hypersplenism. METHODS: Forty-six patients with hepatic cirrhosis accompanied by hypersplenism and portal hypertension received PSE therapy. The variations of hemogram, spleen size, portal vein width, and the complications were observed. RESULTS: The numbers of white blood cells and thrombocytes rose a lot after the treatment and kept on a certain level after 3 months; the red blood cells had no clear variation after the treatment; spleen became much smaller after 3 months; portal vein width reduced to some extent, and no serious complications happened after the treatment. CONCLUSION: PSE is safe and effective for curing cirrhosis together with hypersplenism and portal hypertension.