| 超临界-CO2法萃取苦参中苦参碱的工艺优化 |
| |
| 引用本文： | 刘修树,周晶,何晓丽,方丽波,汤洁. 超临界-CO2法萃取苦参中苦参碱的工艺优化[J]. 中国现代中药, 2012, 14(11): 46-48 |
| |
| 作者姓名： | 刘修树 周晶 何晓丽 方丽波 汤洁 |
| |
| 作者单位： | 1. 合肥职业技术学院,安徽合肥,238000
2. 安徽省中医院,安徽 合肥,230031 |
| |
| 基金项目： | 安徽省教育厅质量工程省级特色专业 |
| |
| 摘 要： | 目的：探讨超临界-CO2法萃取苦参中苦参碱最佳工艺。方法：采用HPLC测定含量，以萃重和苦参碱含量为考察指标，运用单因素和正交试验法优选萃取工艺。结果：选择75％的乙醇作为夹带剂，按4倍量加入，CO2流量对苦参碱萃取量有显著的影响，其次是萃取压力和萃取时间。结论：超临界-CO2法萃取苦参中苦参碱最佳工艺是萃取压力25MPa、萃取温度60℃、萃取时间3h、CO2流量40kg·h。
|
| 关 键 词： | 超临界-CO2法 苦参 苦参碱 工艺优化 |
| 收稿时间： | 2012-01-05 |
Optimization of Extracting Process of Matrine in Sophorae Flavescentis Radix by Supercritical CO2 |
| |
| LIU Xiu-shu,ZHOU Jing,HE Xiao-li,FANG Li-bo and TANG jie. Optimization of Extracting Process of Matrine in Sophorae Flavescentis Radix by Supercritical CO2[J]. Modern Chinese Medicine, 2012, 14(11): 46-48 |
| |
| Authors: | LIU Xiu-shu ZHOU Jing HE Xiao-li FANG Li-bo TANG jie |
| |
| Affiliation: | 1 (1.Hefei Vcational and Technical College,Hefei 238000,China; 2. Traditional Chinese Medical Hospital in Anhui, Hefei 230031, China) |
| |
| Abstract: | Objective： Select a best process of Matrine in Sophorae Flavescentis Radix by supercritical CO2. Methods： HPLC is the method of content determination. Extraction technology was optimized by the extraction weight and the content of Matrine in single factor and orthogonal design. Results： 75% ethanol was elected as entraining agent. Addition capacity is 4 times of volume. Compared with the other three factors, the quantity of flow of CO2 has more influence on extraction, The next influencing factors are pressure and time of extraction. Conclusion： The best extracting process by supercritical CO2 was 25 MPa, 60 ℃, 3 h, quantity of flow of CO2 40 kg·h-1. |
| |
| Keywords: | Supercritical CO2 Sophorae Flavescentis Radix Matrine Optimization of extracting process |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
| 点击此处可从《中国现代中药》浏览原始摘要信息 |
|
点击此处可从《中国现代中药》下载免费的PDF全文 |
|
