丹红注射液联合脑心通胶囊治疗冠心病不稳定型心绞痛的临床疗效观察

目的:观察丹红注射液联合脑心通胶囊治疗冠心病不稳定型心绞痛(UA)患者的临床疗效。方法:治疗组和对照组均常规应用硝酸酯类药物、血管紧张素转换酶抑制剂、钙离子拮抗剂、β受体阻滞剂等治疗。治疗组在此基础上,予静滴丹红注射液和口服脑心通胶囊。结果:疗程结束后,心绞痛和心电图改善情况比较,治疗组明显优于对照组(P<0.05)。治疗组ST-T段降低程度明显减小,与对照组及治疗前比较差异有统计学意义(P<0.05)。心绞痛发作频率及持续时间,治疗组与对照组及治疗前比较差异也有统计学意义(P<0.05)。2组患者在治疗过程中和治疗后均无特异性不良反应。结论:丹红注射液联合脑心通胶囊能减少心绞痛发作次数和心绞痛发作时间,临床效果较好,副作用较少,值得临床进一步推广和应用。

Clinical Observation on Therapeutic Effect of Danhong Injection Combined with Naoxintong Capsule in Treatment of Unstable Angina

Objective ：To observe the clinical effect of Danhong injection combined with Naoxintong capsule treating unstable angina. Methods： The treatment group and the control group were both routinely given nitrates, angiotensin converting enzyme inhibitor, calcium ion antagonist, beta- blocker treatment, etc. On this basis, the treatment group was also intravenously given Danhong injection and orally given Naoxintong capsule. Results： After treatment, the symptoms of angina pectoris and ECG in treatment group were improved, and were remarkably better than control group （ P 〈 0. 05）. The ST - T segment in the treatment group reduced remarkably ,and had statistical differences compared with the control group and before treatment （P 〈 0. 05）. The frequency and duration of angina pectoris attack in the treatment group were significantly decreased than that of control group and before treatment （P 〈 0.05）. There were no specific adverse reactions in both groups during and after treatment. Conclusion： Danhong injection combined with Naoxintong capsule can reduce the frequency and duration time of angina pectoris attack. This therapy has good clinical effect with fewer side effects, and is worth clinical applying further.