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药源性干眼症
引用本文:杨永升,张守康,谢立科.药源性干眼症[J].国际眼科纵览,2012,36(4):245-250.
作者姓名:杨永升  张守康  谢立科
作者单位:中国中医科学院眼科医院,北京,100040
摘    要:药源性干眼症是近年来逐渐被认识的一类药源性眼病,引起此病的药物有十余类上百种,其中常见的有抗胆碱能受体药、抗组胺药、抗抑郁症类药、抗精神病类药、激素类药、抗青光眼类药等。主要机制是药物影响副交感或交感神经系统,支配腺体分泌的通路受到阻断;或药物局部使用引起泪膜不稳定及眼表面异常。防治此类干眼症主要采用停药或换药,对因治疗以及对症处理。

关 键 词:干眼  药源性干眼  药源性疾病

Drug-induced dry eye
YANG Yong-sheng , ZHANG Shou-kang , XIE Li-ke.Drug-induced dry eye[J].International Review of Opthalmology,2012,36(4):245-250.
Authors:YANG Yong-sheng  ZHANG Shou-kang  XIE Li-ke
Institution:. Eye Hospital of China Academy of Chinese Medical Sciences, Beijing 100040, China
Abstract:Druginduced dry eye is gradually recognized by ophthalmologists in recent years. It has been found that more than 10 categories and hundreds of drugs can induce dry eye, which include anticho linergic receptor drugs, antihistamines, antidepressant drugs, antipsychotic drugs, hormone drugs, anti glaucoma drugs, and so on. The main mechanisms include the influence of drugs on the parasympathetic/ sympathetic system so that the secretion pathway of lacrimal gland blocked, or tear film instability and ocular surface abnormalities caused by eye drops or ointments. Preventions and treatments are mainly to stop or change the drugs, etiological treatment and symptomatic treatment.
Keywords:dry eye  drug-induced dry eye  drug-induced eye diseases
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