Evaluation of a monoclonal antibody-based test for detection of Helicobacter pylori-specific antigen in stool samples from mice |
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| Authors: | Crone Julia Symonds Erin Campbell Fiona Butler Ross |
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| Affiliation: | Gastroenterology Unit, Women's and Children's Hospital, North Adelaide, 5006 South Australia, Australia. |
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| Abstract: | A test using monoclonal antibodies for detection of antigen in stool samples was compared with culture and histology for noninfected (n = 25), Helicobacter pylori-infected (n = 25), and Helicobacter felis-infected (n = 6) mice. Sensitivity and specificity were 96%. The monoclonal antibody-based test is therefore a noninvasive technique that is able to diagnose H. pylori infection in mice. |
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