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沙棘油治疗造血功能障碍动物实验及临床研究
引用本文:胡振玉 刘玉林. 沙棘油治疗造血功能障碍动物实验及临床研究[J]. 宁夏医学杂志, 1994, 16(6): 343-347
作者姓名:胡振玉 刘玉林
作者单位:空军西安医院,第四军医大学实验动物研究中心
摘    要:在600余只BALB/C小鼠中建立了造血功能障碍疾病模型,观察了经60CO射线一次全身照射后外周血象、骨髓象和肝、脾、骨髓的病理学变化及死亡曲线;探讨了沙棘油治疗动物中造血功能障碍的机理。与此同时,还先后进行了沙棘油治疗31例各类造血功能障碍疾病病人的临床观察。动物实验结果及临床观察均提示,沙棘油可作为治疗造血功能障碍疾病的有效药物之一。

关 键 词:造血功能障碍 沙棘油 药理学

Hippophae Oil in Treating AplasticHematopoiiesis; Animal Experiment &Clinical Observation
Hu Zhenyu,Guo Wuying,Wang Rui,Zhao Shuxian. Hippophae Oil in Treating AplasticHematopoiiesis; Animal Experiment &Clinical Observation[J]. Ningxia Medical Journal, 1994, 16(6): 343-347
Authors:Hu Zhenyu  Guo Wuying  Wang Rui  Zhao Shuxian
Abstract:compatible models of aplastic hematopoiesis(AH) were made in BALB/c mice, hemogram,myelogram and pathological changes in liver, spleen & bone marrow following 60Co irradiation were obs-erved; and,model-animal experim-ents of treating AH with hippophae oil(Ho) were performed. Meanwh-ile,clinical trials of HO therapyin 31 inpatients of various types of AH were also carried out successi-vely. Results obtained from these animal experiments & clinical obser-vations suggested that HO could serveas an effeetive medicine for treating AH.
Keywords:Aplastic Hematopoie-sis/ther  Hippophae oil/drug eff  Clinical trials  Mice  inbred BALB C  
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