单一应用磷酸钠盐口服溶液在大肠癌术前肠道准备中的临床观察

目的探讨单一应用磷酸钠盐口服溶液在大肠癌术前肠道准备中的清洁效果、不良反应和耐受性。方法将212例需做术前肠道准备的大肠癌患者随机分为四组:A组53例,口服磷酸钠盐口服溶液;B组55例,口服磷酸钠盐口服溶液联合磷酸钠盐灌肠液肛入;C组51例口服聚乙二醇电解质溶液;D组53例,口服硫酸镁溶液。观察4种不同肠道准备方法的肠道清洁有效率、不良反应率和耐受性。结果A组患者的肠道清洁有效率显著优于C组(P=0.031),而与B组、D组相比均无统计学差异(P>0.05)。A组患者在腹胀及恶心发生率方面显著低于D组(P=0.037,0.008),而在腹痛、腹胀、恶心、呕吐方面A组与B组、C组相比均无统计学差异(P>0.05)。A组患者的耐受性显著优于D组(P=0.001),而与B组、C组比较均无统计学差异(P=0.570,0.379)。结论 单一应用磷酸钠盐口服溶液用于大肠癌术前肠道准备的肠道清洁有效率高,且不良反应少,患者耐受性好。

Clinical observation of single oral sodium phosphate in preoperative bowel preparation for colorectal cancer

Objective To explore the cleaning efficacy,tolerability and safety of single oral sodium phosphate in preoperative bowel preparation for colorectal cancer.Methods 212 patients who underwent the operation of colorectal cancer were randomly divided into four groups: A,B,C and D.In A group,53 cases took single oral sodium phosphate.In B group,55 cases were given the combination of oral sodium phosphate and sodium phosphate clyster.51 cases took polyethylene glycol solution(PEG) in group C,and 53 cases was admi...