| 胰腺癌患者血清中巨噬细胞抑制因子-1的大样本临床研究 |
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| 引用本文： | 王小兵,付超,吴凡,田海梅,李艳芬,李茉,程冬婉,常青云,刘珊,齐军,张伟. 胰腺癌患者血清中巨噬细胞抑制因子-1的大样本临床研究[J]. 癌症进展, 2011, 9(4): 367-373 |
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| 作者姓名： | 王小兵 付超 吴凡 田海梅 李艳芬 李茉 程冬婉 常青云 刘珊 齐军 张伟 |
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| 作者单位： | 中国医学科学院,北京协和医学院,肿瘤医院生物检测中心,北京,100021;中国医学科学院,北京协和医学院,肿瘤医院检验科,北京,100021;中国医学科学院,北京协和医学院,肿瘤医院腹部外科,北京,100021 |
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| 基金项目： | 国家高技术研究发展863计划资助项目(项目编号:2008AA022415)中央级公益性科研院所基本科研业务费资助项目 |
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| 摘 要： | 目的 探讨巨噬细胞抑制因子1(MIC-1)在胰腺癌诊断、早期诊断及治疗监测中的临床价值.方法 应用自主研制的MIC-1检测试剂盒检测552例不同临床分期的胰腺癌患者、115例胰腺良性肿瘤患者、21例慢性胰腺炎及200例健康人血清样本中MIC-1水平,并对部分早期肿瘤患者的病程进行随访监测;应用罗氏Cobas 601电化...
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| 关 键 词： | 巨噬细胞抑制因子-1 肿瘤标志物 胰腺癌 临床价值 |
Clinical research of serum macrophage inhibitory cytokine-1 in large samples of patients with pancreatic cancer |
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| Wang Xiaobing,Fu Chao,Wu Fan,Tian Haimei,Li Yanfen,Li Mo,Cheng Dongwan,Chang Qingyun,Liu Shan,Qi Jun,Zhang Wei. Clinical research of serum macrophage inhibitory cytokine-1 in large samples of patients with pancreatic cancer[J]. Oncology Progress, 2011, 9(4): 367-373 |
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| Authors: | Wang Xiaobing Fu Chao Wu Fan Tian Haimei Li Yanfen Li Mo Cheng Dongwan Chang Qingyun Liu Shan Qi Jun Zhang Wei |
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| Affiliation: | Wang Xiaobing1 Fu Chao2 Wu Fan3 Tian Haimei1 Li Yanfen1 Li Mo 1Cheng Dongwan1 Chang Qingyun1 Liu Shan1 Qi Jun2 Zhang Wei1 1 Detection Center of Tumor Biology,2Clinical Laboratory,3Department of Abdominal Surgical Oncology,Cancer Institute & Hospital,Chinese academy of Medical Sciences & Peking UnionMedical College,Beijing 100021,China |
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| Abstract: | Objective To investigate the clinical value of macrophage inhibitory cytokine-1(MIC-1)in the diagnosis,early diagnosis,and treatment monitoring of pancreatic cancer.Methods serum samples form 522 patients with different clinical stages of pancreatic cancer,115 patients with benign pancreatic tumor,21 patients with chronic pancreatitis and 200 healthy persons were analyzed by self-made MIC-1 assay kit.And the patients at early stage were followed up.CEA and CA19-9 were analyzed by Roche Cobas 601 ECL analyze... |
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| Keywords: | macrophage inhibitory cytokine-1 tumor marker pancreatic cancer clinical value |
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