氟硅酮丙烯酸脂材料制作角膜塑形镜控制近视效果及其安全性

背景：氟硅酮丙烯酸脂透气性材料成为制作角膜塑形镜的理想材料,其对眼屈光和眼生理的影响受到关注。目的：研究角膜塑形术控制近视发展的临床效果及安全性。方法：观察18例35眼佩戴1年角膜塑形镜的青少年中、低度近视裸眼视力、屈光度变化、眼轴长度、角膜内皮计数、眼压、角膜Q值等变化。结果与结论：1年后裸眼视力与佩戴前矫正视力比较差异无显著性意义(t=-0.27、P=0.78);佩戴前后1年屈光度、眼轴长度、角膜内皮计数、眼压比较差异无显著性意义(t=1.37、P=0.18;t=-0.94、P=0.35;t=-0.52、P=0.6;t=1.00、P=0.32);佩戴前后1年角膜Q值比较差异有显著性意义(t=-8.03、P=0.00)。提示氟硅酮丙烯酸脂透气性材料角膜塑形镜控制近视安全、有效,对眼生理影响小。

Effect and safety of orthokeratology made of fluorosilicone acrylate on myopia control

BACKGROUND: Fluorosilicone acrylate is a perfect plastic material for orthokeratology, and its influence on diopter and physiology of the eye is attracted.OBJECTIVE: To study the clinical safety and effects of orthokeratology to control myopia development. METHODS: The clinical data of 18 patients (35 eyes) wearing orthokeratology contact lens (Ortho-k CL) for 1 year were analyzed in low-and middle-degree myopia of the teenage, including uncorrected visual acuity (UCVA), diopter, axial length, the number of corneal endothelial cells, intraocular pressure, cornea Q value.RESULTS AND CONCLUSION: There was no significant difference in the UCVA after wearing Ortho-k CL for 1 year to corrected visual acuity before wearing (t=-0.27, P=0.78). Compared to before wearing Ortho-k CL, there was no significant difference in diopter, axial length, the number of corneal endothelial cells, intraocular pressure at 1 year after wearing (t=1.37, P=0.18; t=-0.94, P=0.35; t=-0.52, P=0.6; t=1.00, P=0.32). There was significant difference in cornea Q value (t=-8.03, P=0.00) between before and after wearing Ortho-k CL. Results showed that fluorosilicone acrylate Ortho-k CL is effective and safe to control myopia development with little influence on eye physiology.