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阿立哌唑与利培酮治疗老年精神分裂症的对照研究
引用本文:石保青,蒋成娣,李燕.阿立哌唑与利培酮治疗老年精神分裂症的对照研究[J].中国民康医学,2011,23(16):1971+1976.
作者姓名:石保青  蒋成娣  李燕
作者单位:河南省洛阳荣康医院,河南,洛阳,471013
摘    要:目的:探讨阿立哌唑与利培酮治疗老年精神分裂症的疗效与安全性。方法:将76例老年精神分裂症患者随机分成阿立哌唑组和利培酮组各38例。对两组患者均进行12周的治疗观察。于治疗前及治疗1、2、4、8、12周末用阳性与阴性症状量表(PANSS)评定疗效,副反应量表(TESS)、实验室及诊断仪器检查评定药物安全性。结果:阿立哌唑组显效率60.2%,利培酮组显效率60.9%,两组疗效差异无显著性。两组不良反应均较轻,阿立派唑组更轻于利培酮组。结论:阿立哌唑和利培酮治疗精神分裂症疗效均较好,但阿立哌唑的药物副作用较小。

关 键 词:阿立哌唑  利培酮  精神分裂症

Comparative study of Aripiprazole and Risperidone in the treatment of senile schizophrenia
SHI Bao-qing,JIANG Cheng-di,LI Lan.Comparative study of Aripiprazole and Risperidone in the treatment of senile schizophrenia[J].medical journal of chinese peoples health,2011,23(16):1971+1976.
Authors:SHI Bao-qing  JIANG Cheng-di  LI Lan
Institution:SHI Bao-qing,JIANG Cheng-di,LI Lan(Luoyang Rongkuang Hospital,Luoyang 471013,China)
Abstract:Objective:To study the curative effect and safety of Aripiprazole and Risperidone in the treatment of senile schizophrenia.Methods:76 patients with senile schizophrenia were allocated to two groups randomly;38 patients took Aripiprazole and others took Risperidone.The therapeutics effects and side effects were assessed with PANSS and TESS before the treatment,1,2,4,8,and 12weeks later.Results:The efficacy rate of Aripiprazole was 60.2%,and Rsperidone group was 60.9%.There was no significant difference in ef...
Keywords:Aripiprazole  Risperidone  Schizophrenia  
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