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Mohnarin2010年度报告:东北地区细菌耐药监测
引用本文:张伟丽,孔海深,杨青,陈晓,魏泽庆,陈云波,沈萍,肖永红,李兰娟.Mohnarin2010年度报告:东北地区细菌耐药监测[J].中华医院感染学杂志,2011,21(23):4903-4908.
作者姓名:张伟丽  孔海深  杨青  陈晓  魏泽庆  陈云波  沈萍  肖永红  李兰娟
作者单位:浙江大学医学院附属第一医院传染病诊治国家重点实验室,浙江杭州,310003
摘    要:目的 调查分析东北地区2010年临床分离细菌的分布以及对抗菌药物的耐药性.方法 2010年东北地区6所医院采用K-B法或自动化仪器法对临床分离细菌进行药物敏感试验,依据CLSI 2010年标准,采用WHO-NET5.5软件进行统计分析.结果 东北地区6所医院共分离细菌18 150株,其中革兰阴性菌14 029株,占77.3%,革兰阳性菌共4121株,占22.7%;产超广谱β-内酰胺酶(ESBLs)大肠埃希菌、产酸克雷伯菌、肺炎克雷伯菌和奇异变形菌的检出率分别为86.9%、78.4%、75.3%和54.3%;肠杆菌科细菌对亚胺培南仍保持较高的敏感率(>90.0%);铜绿假单胞菌、鲍氏不动杆菌和洋葱伯克霍尔德菌对美罗培南的耐药率分别为20.1%、64.2%和14.6%;MRSA和MRSCN检出率分别为60.4%和74.0%;未检测到耐万古霉素葡萄球菌;屎肠球菌和粪肠球菌对万古霉素的耐药率为1.3%、0.7%;对替考拉宁的耐药率为1.6%、0.5%.结论 东北地区出现耐万古霉素肠球菌、耐碳青霉烯类肠杆菌科细菌及多药耐药非发酵菌增加,应引起重视.

关 键 词:东北  2010年  细菌耐药性  革兰阴性菌  革兰阳性菌

Mohnarin report of 2011:bacterial distribution and resistance in northeast China
ZHANG Wei-li , KONG Hai-shen , YANG Qing , CHEN Xiao , WEI Ze-qing , CHEN Yun-bo , SHEN Ping , XIAO Yong-hong , LI Lan-juan.Mohnarin report of 2011:bacterial distribution and resistance in northeast China[J].Chinese Journal of Nosocomiology,2011,21(23):4903-4908.
Authors:ZHANG Wei-li  KONG Hai-shen  YANG Qing  CHEN Xiao  WEI Ze-qing  CHEN Yun-bo  SHEN Ping  XIAO Yong-hong  LI Lan-juan
Institution:ZHANG Wei-li,KONG Hai-shen,YANG Qing,CHEN Xiao,WEI Ze-qing,CHEN Yun-bo,SHEN Ping,XIAO Yong-hong,LI Lan-juan (The First Affiliated Hospital,College of Medicine,Zhejiang University,Hangzhou,Zhejiang 310003,China)
Abstract:OBJECTIVE To investigate clinical bacterial distribution and antimicrobial resistance in northeast China in 2010. METHODS Clinical bacterial isolates were collected from 6 hospitals in northeast China and antibiotic susceptibility test was carried out by means of K-B disk diffusion or automatic bacterial identifying system.The data was analyzed with WHONET5.5 software referring to CLSI 2010 breakpoints. RESULTS Totally 18 150 strains were isolated from 6 hospitals in northeast China,which consisted of 14 02...
Keywords:Northeast China  2010  Bacterial resistance  Gram-negative bacteria  Gram-positive bacteria  
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