| 14例儿童肝母细胞瘤综合治疗的疗效观察 |
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| 引用本文： | 魏艇,杨体泉,罗意革,董淳强.14例儿童肝母细胞瘤综合治疗的疗效观察[J].中国当代儿科杂志,2009,11(6):456-459. |
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| 作者姓名： | 魏艇 杨体泉 罗意革 董淳强 |
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| 作者单位： | 魏艇，杨体泉，罗意革，董淳强 |
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| 摘 要： | 目的：肝母细胞瘤是儿童时期最为常见的原发性肝脏恶性肿瘤。新辅助化疗﹢手术﹢术后化疗已成为肝母细胞瘤治疗的基本原则。该文旨在总结肝母细胞瘤综合治疗的疗效，进而探讨合理治疗的策略。方法：回顾性分析14例儿童肝母细胞瘤患者的临床资料，并追踪随访其治疗后的生存状况。结果：12例肝母细胞瘤患儿接受全程治疗，中位随访时间为18个月（1.5~74月）。9例无瘤存活，1例死亡，1例肿瘤转移，1例未发现肿瘤残留但术后甲胎蛋白持续不降。结论：手术及规范化疗能有效提高儿童肝母细胞瘤患者的生存率。［中国当代儿科杂志，2009，11（6）：456-459］
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| 关 键 词： | 肝母细胞瘤 化疗 手术 甲胎蛋白 儿童 |
Treatment and outcome of 14 children with hepatoblastoma |
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| WEI Ting,YANG Ti-Quan,LUO Yi-Ge,DONG Chun-Qiang.Treatment and outcome of 14 children with hepatoblastoma[J].Chinese Journal of Contemporary Pediatrics,2009,11(6):456-459. |
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| Authors: | WEI Ting YANG Ti-Quan LUO Yi-Ge DONG Chun-Qiang |
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| Institution: | WEI Ting, YANG Ti-Quan, LUO Yi-Ge, DONG Chun-Qiang |
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| Abstract: | Objective To assess the outcome of childhood hepatoblastoma after a combination therapy of resection and chemotherapy.Methods The clinical data of 14 children with hepatoblastoma was retrospectively reviewed. Their long-term survival was followed-up.Results Twelve cases received surgery and planned chemotherapy. The follow-up duration averaged 18 months (range 1.5-74 months). Nine survived free of events, 1 died, 1 survived with multiple lung metastases, and 1 with increased alpha-fetoprotein (AFP) content ... |
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| Keywords: | Hepatoblastoma Chemotherapy Surgery Alpha-fetoprotein Child |
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