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| 不同隔姜灸治时间对慢性浅表性胃炎脾胃虚寒证患者血清中SOD和MDA的影响 | |
| 引用本文： | 易展,刘密,常小荣,严洁,谢华,王德军,艾坤,刘未艾.不同隔姜灸治时间对慢性浅表性胃炎脾胃虚寒证患者血清中SOD和MDA的影响[J].中国实验方剂学杂志,2012,18(23):301-304. |
| 作者姓名： | 易展 刘密 常小荣 严洁 谢华 王德军 艾坤 刘未艾 |
| 作者单位： | 1. 湖南中医药大学针灸推拿学院,长沙,410007 2. 深圳市福田区中医院,广东深圳,518000 3. 郴州市第一人民医院,湖南郴州,423000 |
| 基金项目： | 国家自然科学基金课题(30973802);湖南省中医药科研计划课题(2010101);长沙市科技计划重点项目(K1005020-31) |
| 摘 要： | 目的:探讨隔姜灸不同灸治时间对慢性浅表性胃炎脾胃虚寒证患者血清中超氧化物歧化酶(superoxide dismutase,SOD)与丙二醛(malondialdehyde,MDA)的影响。方法:将45例浅表性胃炎脾胃虚寒证患者随机分为隔姜灸20 min组(A组)15例、隔姜灸40 min组(B组)15例、雷尼替丁组(C组)15例。治疗组每天隔姜灸1次,10 d为1个疗程,疗程间休息1 d,共治疗2个疗程;对照组服用雷尼替丁每次0.15 g,1 d 2次,连续服药10 d为1个疗程,疗程间休息1 d,共服药2个疗程。于实验治疗前、治疗后分别抽血取血清检测SOD,MDA的含量,以此观察隔姜灸的疗效及对SOD和MDA的影响。结果:①3组的SOD含量:在各组治疗后与其治疗前比较均有显著性差异。B组治疗前后SOD含量的增加,与A,C两组比较均有显著性差异(P<0.05)。②3组的MDA含量:在各组治疗后与其治疗前比较均有显著性差异。但组间比较,各组治疗前后MDA含量没有显著性差异。结论:隔姜灸与雷尼替丁均能使血清中抗氧化酶SOD活性升高而自由基MDA水平降低,且隔姜灸40min提高SOD水平效果显著,明显高于隔姜灸20 min和雷尼替丁对SOD的作用。证明隔姜灸对浅表性胃炎脾胃虚寒证患者氧自由基产生与清除的酶系统具有良性调节作用,隔姜灸治疗浅表性胃炎脾胃虚寒证取效可能与此机制有关。 |
| 关 键 词： | 隔姜灸 浅表性胃炎 脾胃虚寒证 超氧化物歧化酶 丙二醛 |
| 收稿时间： | 2012/6/24 0:00:00 |
Influence of Serum SOD and MDA by Moxibustion on Ginger Therapy for Chronic Superficial Gastritis Spleen-Stomach Vacuity Cold Patients with Differents Time |
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| YI Zhan,LIU Mi,CHANG Xiao-rong,YAN Jie,XIE Hu,WANG De-jun,AI Kun and LIU Wei-ai.Influence of Serum SOD and MDA by Moxibustion on Ginger Therapy for Chronic Superficial Gastritis Spleen-Stomach Vacuity Cold Patients with Differents Time[J].China Journal of Experimental Traditional Medical Formulae,2012,18(23):301-304. | |
| Authors: | YI Zhan LIU Mi CHANG Xiao-rong YAN Jie XIE Hu WANG De-jun AI Kun and LIU Wei-ai |
| Institution: | College of Acu-Moxibustion and Tuina, Hunan University of Chinese Medicine, Changsha 410007, China;College of Acu-Moxibustion and Tuina, Hunan University of Chinese Medicine, Changsha 410007, China;College of Acu-Moxibustion and Tuina, Hunan University of Chinese Medicine, Changsha 410007, China;College of Acu-Moxibustion and Tuina, Hunan University of Chinese Medicine, Changsha 410007, China;College of Acu-Moxibustion and Tuina, Hunan University of Chinese Medicine, Changsha 410007, China;Shenzhen Futian Hospital of Chinese Medicine, Shenzhen 518000, China;First People's Hospital of Chenzhou City, Chenzhou 423000, China;College of Acu-Moxibustion and Tuina, Hunan University of Chinese Medicine, Changsha 410007, China |
| Abstract: | |
| Keywords: | Moxibustion on ginger chronic superficial gastritis spleen-stomach vacuity cold superoxide-dismutase malondialdehyde |
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