局限性Castleman病的CT和MRI表现

目的 探讨局限性Castleman病（Localized Castleman Disease，LCD）的CT和MRI影像学表现。方法回顾性分析经手术和病理证实的7例LCD的CT和MRI（7例均行CT检查，仅有2例行MRI检查）表现。结果本组7例LCD经病理证实：透明血管型6例，浆细胞型1例。位于中纵隔2例、右肺门1例、后纵隔3例、腹膜后1例。透明血管型：CT表现为类圆形软组织肿块，密度均匀，包膜完整，边缘清晰光整，可伴分支状和斑点状钙化，CT增强呈持续显著强化。MRI检查2例均为透明血管型，T1WI病灶呈等、高信号，T2WI为均匀高信号，钙化呈低信号，增强与CT相似。浆细胞型CT表现：密度不均，其内见不规则坏死，增强中度不均匀强化。结论 根据影像学显著持续强化的特点，有助于Castleman病诊断和鉴别诊断。

Localized Castleman''''s disease:CT and MRI findings

Objective To study the CT and MRI findings of localized Castleman＇s disease （LCD）. Methods The CT （n=7） and MRI （n=2） appearance of LCD （n=7） confirmed by pathology and operation were retrospectively analyzed. Results Hyaline-vascular type（n=6） and plasma cell type （n= 1） were confirmed by pathology in LCD（n=7 ）. They were located in middle mediastinum （n=2）, hilum pulmonis （n=1）, posterior mediastinum （n=3）, retro-peritoneum （n=1）. Hyaline-vascular type focuses in CT scanning were manifested as round shape soft tissue masses, with homogeneous density, integrity envelope, distinct margin, and chaperonage arborizing and spot calcification. Marked persistent enhancement was apparent on contrast CT. MRI findings of hyaline-vascular type （n=2） was slightly isointense or hyperintense on T1WI, homogeneous hyperintense on T2WI, similar enhancement with CT after contrast. Plasma cell type focus were unhomogeneous density with abnormity necrosis, media and unhomogeneous enhancement after contrast. Conelusion Marked persistent enhancement of LCD would be helpful to diagnosis and differential diagnosis in Castleman＇s disease.