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Comparative analysis of progesterone and estradiol reception in human myoma
Authors:P V Sergeev  E N Kareva  N Yu Tkacheva
Institution:(1) Department of Molecular Pharmacology and Radiobiology, Biomedical Faculty, Russian State Medical University, Moscow
Abstract:Cytosolic and plasma membrane receptors for progesterone and estradiol are studied in myomatous nodes (MN) and in histologically unaltered myometrium (HUM) against the background of myoma. The level of cytosolic receptors for both hormones is higher in the myoma cells than in the essentially healthy myometrium. In the plasma membranes the progresterone reception is reduced and the estradiol reception is unchanged compared with HUM. Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 118, N o 7, pp. 33–34, July, 1994
Keywords:progesterone receptors                      estradiol receptors                      plasma membrane                      myoma
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