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Spectral analysis and acoustic transmission of mitral and aortic valve closure sounds in dogs
Authors:Dr L. -G. Durand  Y. -E. Langlois  T. Lanthier  R. Chiarella  P. Coppens  S. Carioto  S. Bertrand-Bradley
Affiliation:1. Laboratory of Biomedical Engineering, Clinical Research Institute of Montreal, University of Montreal, 110 West Pine Avenue, H2W 1R7, Montreal, Quebec, Canada
2. Department of Surgery, H?tel-Dieu de Montréal Hospital, 3840 St-Urbain, H2W 1T8, Montreal, Quebec, Canada
3. Department of Medicine, Faculty of Veterinary Medicine, University of Montreal, 3200 Sicotte Street, J2S 7C6, St-Hyacinthe, Quebec, Canada
4. Medtronic of Canada, 1 Place du Commerce, Suite 170, Ile des Soeurs, H3E 1A2, Verdun, Quebec, Canada
Abstract:A surgical protocol was designed to implant, in seven dogs, a programmable sequential atrioventricular pacemaker after destruction of the bundle of His to produce a chronic heart block. The heart rate and P-R interval were then varied independently and their influence on the spectra and acoustic transmission of the mitral M1 and aortic A2 valve closure sounds was studied. Results indicate that the major effects of varying the P-R interval are a strong change in the intensity of M1 and modifications of its acoustic transmission across the heart/thorax acoustic system. No similar influence is observed on the intensity and acoustic transmission of A2. Varying the heart rate has a small effect of the intensity of M1 but none on the intensity of A2. In addition, changes in either the P-R interval or the heart rate do not seem to modify the spectral profile of the intracardiac and thoracic M1 and A2 components.
Keywords:Aortic valve  Heart rate  Heart sounds  Heart/thorax acoustic system  Mitral valve  P-R interval  Spectral analysis
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