Immunogenicity of a heat-treated recombinant DNA hepatitis B vaccine |
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Authors: | M Just R Berger |
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Affiliation: | University Children's Hospital, Basel, Switzerland. |
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Abstract: | The effect of heating on the reactogenicity and the immunogenicity of a recombinant DNA hepatitis B vaccine was examined. Treatment of this vaccine for one week at 37 degrees C did not significantly alter these properties when compared to vaccine stored at 4 degrees C. These results have important implications in countries where facilities for the transport and handling of vaccines are often inadequate. |
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