2001-2010年我国伤害预防病例对照研究及队列研究文献质量评价

目的评价2001-2010年我国公开发表的伤害预防病例对照研究和队列研究文献的质量。方法文献来源于四个主要的中文数据库和两个英文数据库。采用Newcastle-Ottawa-Scale（NOS）工具分别对纳入的伤害预防病例对照研究和队列研究文献进行方法学质量评价。结果 2001-2010年我国伤害预防病例对照研究和队列研究文献分别有84篇和13篇。病例对照研究中,职业人员和儿童青少年分别占45.2%和36.9%,伤害类型中,多种伤害占71.4%。队列研究中,儿童青少年占46.2%,伤害类型中,多种伤害占92.3%。病例对照研究的方法学质量得分均在5分及以上,平均（6.1±0.7）分;但研究在＂暴露因素的确定＂、＂无应答率＂以及＂病例的确定是否恰当＂条目上得分较低。队列研究的方法学质量得分以6分和7分为主,平均（6.3±0.9）分;但研究在＂结局指标的评价＂条目上得分较低。结论我国的伤害病例对照研究和队列研究数量较少,研究人群以儿童青少年和职业人员为主,伤害类型以多种伤害为主,质量相对较高。

Quality assessment of case-control and cohort studies on injury prevention in China, 2001-2010

Objective To evaluate the methodological quality of published case-control and cohort studies on inju- ry prevention in China from 2001 to 2010. Methods Publications between 2001 and 2010 were retrieved from four major Chinese electrical databases and two international electrical databases. Newcastle-Ottawa-Scale （NOS） was used to evalu- ate the methodological quality of searched articles. Results From 2001 to 2010, the numbers of case-control studies and cohort studies about injury prevention were 84 and 13 in China, respectively. Occupational population, children and ado- lescents accounted for 45.2% and 36. 9% of case-control studies, respectively. Multiple injuries were mostly studied, ac- counting for 71.4% of case-control studies. 46. 2% of published cohort studies focused on children and adolescents, and 92. 3% of them targeted multiple injuries. All of published case-control studies scored over 5.0 points. The mean quality scores of case-control studies was 6. 1 points （ standard deviation： 0. 7 points）. Many studies had low scores in the items of ＂ascertainment of exposure＂, ＂non-response rate＂ and ＂adequate case definition＂. Most of published cohort studies were scored 6-7 points. The mean quality scores was 6. 3 points （standard deviation： 0. 9 points）. The cohort studies had low scores in the item of ＂assessment of outcome＂. Conclusions Published case-control studies and cohort studies about inju- ry prevention were limited in China between 2001 -2010. Studies were focused on children, adolescents and occupational population, mostly on multiple injuries. The methodological quality of published case-control studies and cohort studies is relatively high.