REM sleep deprivation increases aggressiveness in male rats.

As a test of the hypothesis that REM deprivation increases aggressiveness in rats, the effects of two and four days of REM deprivation were measured on the frequency and latency with which male rats attack mice. The results showed that REM deprivation increased the frequency of attacks, the muricide rate, and the latency to first attack in a “dose-related” fashion. To a degree these behaviors persisted through a 21-day recovery period.