牙周炎龈沟液免疫球蛋白含量的测定

用改良刻度毛细管收集龈沟液(GCF)，用单扩法测定了50名健康人(H)和32名成人型牙周炎CAP)龈沟液和血清中的IgG、IgA含量．结果：H组GCF中IgG为1．96g／L，是血清的19％。IgA未能测出．AP组GCF中IgG、IgA分别为7．21g／L和0．83g／L．是血清的71％和61％．AP组GCF中IgG与牙龈指数(GI)有正相关．提示GCF中IgG含量与局部炎症程度有关．本研究首次报道了健康人GCF中IgG含量．为研究GCF中Ig含量提供了一个正常值参数。

Study on the levels of immunoglobulin in gingival cervicular fluid.]

The levels of IgG,IgA in gingival cervicular fluid (GCF) and serum were measured by immunodiffusion method.GCF was collected in improved and graduated capillaries from 50 healthy persons and 32 adult periodontitis patients (AP).The result showed that the level of IgG in GCF of healthy persons was 1.96g/L and the ratio of IgG in GCF to that in serum was 19%.The level of IGA in GCF of healthy persons was not available.In AP,the levels of IgG,IgA in GCF were 7.2g/L,0.83g/L and the ration of IgG and IgA in GCF to those in serum were 71%,61% respectively.Rank correlation between Ig and clinic index in AP showed thant only the level of IgG in GCF had positive correlation with GI.This study reported for the first time the level of IgG in GCF of healthy persons and suggested that the level of IgG in GCF had positive correlation with degree of inflammation in gingiva.