| 在位子宫内膜中神经纤维的病理检查对诊断子宫内膜异位症的价值 |
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| 引用本文： | 郭广玲,陈双郧,张春莲,冯丽华,魏振彤,罗仪. 在位子宫内膜中神经纤维的病理检查对诊断子宫内膜异位症的价值[J]. 中国综合临床, 2009, 25(8). DOI: 10.3760/cma.j.issn.1008-6315.2009.08.039 |
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| 作者姓名： | 郭广玲 陈双郧 张春莲 冯丽华 魏振彤 罗仪 |
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| 作者单位： | 1. 郧阳医学院附属太和医院,湖北省十堰市,442000
2. 吉林大学第一临床医院 |
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| 摘 要： | 目的 研究在位子宫内膜中神经纤维的病理检查对诊断子宫内膜异位症的价值.方法 前瞻性分析65例痛经患者行诊断性刮宫,用免疫组织化学技术,使用多克隆家兔抗体PGP 9.5染色标记子宫在位内膜,分析神经纤维密度,同时对所有患者进行腹腔镜探查.结果 通过对在位子宫内膜中神经纤维的病理检查诊断子宫内膜异位症的灵敏度、特异性和准确性均为100%,阳性预测值、阴性预测值均为100%.结论 在位子宫内膜中神经纤维的病理检查是诊断子宫内膜异位症的可靠的手段.
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| 关 键 词： | 子宫内膜异位症 在位子宫内膜 神经纤维 |
Evaluation of the relative efficacy of endometrial curettage for diagnosis of endometriosis by the detection of eutopic endometrial nerve fibers |
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| GUO Guang-ling,CHEN Shuang-yun,ZHANG Chun-lian,FENG Li-hua,WEI Zhen-tong,LUO Yi. Evaluation of the relative efficacy of endometrial curettage for diagnosis of endometriosis by the detection of eutopic endometrial nerve fibers[J]. Clinical Medicine of China, 2009, 25(8). DOI: 10.3760/cma.j.issn.1008-6315.2009.08.039 |
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| Authors: | GUO Guang-ling CHEN Shuang-yun ZHANG Chun-lian FENG Li-hua WEI Zhen-tong LUO Yi |
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| Abstract: | Objective To evaluate endometrial biopsy and curettage in detecting small nerve fibers in eutopic endometrium for diagnosis of endometriosis.Methods Endometrial biopsies and curettings were taken in 65 women with menorrhalgia.Endometrial nerve fibers were immunohistochemically detected using the pan-neuronal marker PGP 9.5.All patients underwent laparoseopie approach.Results The specificity,sensitivity,positive and negative predictive value were 100% of endometrial biopsy and curettings for diagnosis of endometriosis.Condusions Careful endometrial biopsy combined with immunohistochemical staining for nerve fibers may be a reliable means of diagnosing or excluding endometriosis. |
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| Keywords: | Endometriosis Eutopic endometrium Nerve fibres |
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