光学相干断层扫描血管成像技术在青光眼诊治中的研究进展

青光眼是全球不可逆盲的主要原因,但其具体的病理生理学仍不太清楚.目前认为血液动力学改变是青光眼病理生理学的关键因素之一.光学相干断层扫描血管成像技术(OCTA)是一种新的成像技术,使视网膜和脉络膜毛细血管可视化,并使用新颖的算法生成高分辨率图像、量化视网膜和脉络膜的血管密度和血流.本文对OCTA测量视网膜血管密度的变化在青光眼诊治中的研究进展进行综述,为临床使用OCTA诊断青光眼、评价病情严重程度提供参考.

Development of optical coherence tomography angiography in the diagnosis and treatment of glaucoma

Glaucoma is the leading cause of irreversible blindness worldwide. Its specific pathophysiology is still not clear. Currently hemodynamic alterations are regarded as one of the key factors in the pathophysiology of glaucoma. Optical coherence tomography angiography(OCTA)is a new imaging technique that enables visualization of the retinal and choroidal microvasculature, and with novel algorithms generates high resolution images and quantifies vessel density and blood flow of the retina and choroid. We reviewed the recent advances in the diagnosis and treatment of glaucoma measured using OCTA,which provides a reference for diagnosis of glaucoma and evaluation of glaucoma severity.