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| 对比分析99mTc-MDP SPECT与18F-NaF PET/CT术前诊断肺癌骨转移的价值 | |
| 引用本文： | 饶良俊,王晓燕,陈志丰,罗炳棋,张祥松,史新冲,易畅.对比分析99mTc-MDP SPECT与18F-NaF PET/CT术前诊断肺癌骨转移的价值[J].中国医学影像技术,2012,28(12):2233-2238. |
| 作者姓名： | 饶良俊 王晓燕 陈志丰 罗炳棋 张祥松 史新冲 易畅 |
| 作者单位： | 中山大学附属第一医院核医学科,广东广州,510080 |
| 摘 要： | 目的 对比分析99mTc-亚甲基二膦酸盐(MDP) SPECT与18F-氟化钠(NaF) PET/CT术前诊断肺癌骨转移灶的临床价值.方法 回顾性分析274例肺癌患者,其中107例接受18 F-NaF PET/CT检查,167例接受99mTc-MDP SPECT检查,以病理学结果或随访结果作为标准进行分析.结果 107例肺癌术前18 F-NaF PET/CT显像中,2例骨骼病灶性质待定；167例99mTc-MDP SPECT显像中,18例骨骼病灶性质待定.18F-NaF PET/CT和99mTc-MDP SPECT术前诊断肺癌骨转移灶的灵敏度分别为100％(32/32)和87.72％(50/57),前者高于后者(P=0.046),特异度分别为98.67％(74/75)和92.73％(102/110),差异无统计学意义(x2=2.237,P=0.135)；二者的准确率分别为99.07％(106/107)和91.02％(152/167),前者高于后者(x2=6.287,P=0.012).结论 18F-NaF PET/CT骨显像术前评价肺癌骨转移较99mTc-MDP SPECT的灵敏度和准确率高,是肺癌术前评价骨转移的较好方法. |
| 关 键 词： | 肺肿瘤 肿瘤转移 体层摄影术 X线计算机 体层摄影术 发射型计算机 单光子 正电子发射型体层摄影术 99m锝亚甲基二磷酸 18F-氟化钠 |
| 收稿时间： | 3/3/2012 12:00:00 AM |
| 修稿时间： | 4/4/2012 12:00:00 AM |
Comparison of preoperative 99mTc-MDP SPECT and 18F-NaF PET/CT in diagnosis of bone metastases in patients with lung cancer |
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| RAO Liang-jun,WANG Xiao-yan,CHEN Zhi-feng,LUO Bing-qi,ZHANG Xiang-song,SHI Xin-chong and YI Chang.Comparison of preoperative 99mTc-MDP SPECT and 18F-NaF PET/CT in diagnosis of bone metastases in patients with lung cancer[J].Chinese Journal of Medical Imaging Technology,2012,28(12):2233-2238. |
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| Authors: | RAO Liang-jun WANG Xiao-yan CHEN Zhi-feng LUO Bing-qi ZHANG Xiang-song SHI Xin-chong and YI Chang |
| Institution: | Department of Nuclear Medicine, the First Affiliated Hospital, Sun Yat-Sen University, Guangzhou 510080, China;Department of Nuclear Medicine, the First Affiliated Hospital, Sun Yat-Sen University, Guangzhou 510080, China;Department of Nuclear Medicine, the First Affiliated Hospital, Sun Yat-Sen University, Guangzhou 510080, China;Department of Nuclear Medicine, the First Affiliated Hospital, Sun Yat-Sen University, Guangzhou 510080, China;Department of Nuclear Medicine, the First Affiliated Hospital, Sun Yat-Sen University, Guangzhou 510080, China;Department of Nuclear Medicine, the First Affiliated Hospital, Sun Yat-Sen University, Guangzhou 510080, China;Department of Nuclear Medicine, the First Affiliated Hospital, Sun Yat-Sen University, Guangzhou 510080, China |
| Abstract: | |
| Keywords: | Lung neoplasms Neoplasm metastasis Tomography X-ray computed Tomography emission-computed single-photon Positron-emission tomography Technetium Tc 99m medronate 18F-NaF |
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