The effect of sleep deprivation and recovery sleep on plasma corticosterone in the rat |
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| Authors: | I. Tobler R. Murison R. Ursin H. Ursin A.A. Borbély |
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| Affiliation: | 1. Institute of Pharmacology, University of Zürich, Gloriastrasse 32, 8006 Zürich Switzerland;1. Institute of Physiological Psychology, University of Bergen, Årstadtveien 21 Bergen Norway;7. Institute of Physiology, University of Bergen, Årstadtveien 19, N-5000 Bergen Norway |
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| Abstract: | The effect of 24-h sleep deprivation by forced locomotion on plasma corticosterone was investigated in the rat. Corticosterone was slightly elevated after 21.5 h sleep deprivation, but did not differ from controls after a 2.5-h recovery period. An acute 20-min forced locomotion period caused a marked rise in plasma corticosterone. It is concluded that stress is not a major factor contributing to the massive effects of sleep deprivation on sleep parameters. |
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| Keywords: | sleep-deprivation stress corticosterone rat |
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