支原体感染与新生儿疾病关系的研究

目的　研究支原体感染与新生儿疾病之间的关系。方法　采用nPCR对 15 6例新生儿患儿及 5 0例正常新生儿的咽拭子 ,进行解脲脲原体 (Uu)、人型支原体 (Mh)、生殖支原体 (Mg)和发酵支原体 (Mf)特异性核酸检测。 结果　 15 6例新生儿患儿中检出Mh ,Mu ,Mg和Mf的阳性率分别为 84 .6 % ,4 6 .7% ,1.92 % ,0 %。 (Uu +Mg)双重同时感染率为 4 0 .3%(6 3/ 15 6 ) ,(Uu +Mh +Mg)三重感染率为 1.92 % (3/ 15 6 )。 5 0例正常新生儿仅 1例检出Uu。结论　同新生儿疾病支原体感染显著相关。

Relationship between mycoplasma infection and newborn disease

To observe the relation of mycoplasma infection with newborn disease, the specific nucleic acids in the throat swab specimens from 156 cases of patients with newborn diseases and 50 normal newborns were investigated by means of nested polymerase chain reaction (nPCR). It was found that the positive detection rates for Mycoplasma hominis(Mh), Ureaplasma urealytica,(Uu) Mycoplasma genitalium(Mg) and Mycoplasma fermentans(Mf) were 84.6% (132/156), 46.76% (73/156), 1.92% (3/156) and 0% (0/156) in the newborn disease group, but it was only 2% (1/50) in the normal control group. The positive rates for double infections(Uu+Mg) and trip infections(Uu+Mh+Mg) were 40.3% (63/156) and 1.92% (3/156) respectively. It is concluded that the mycoplasma infection is related to the occurrence of newborn diseases.