Complete response of bony metastatic bladder urothelial cancer to neoadjuvant chemotherapy and cystectomy |
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Authors: | Joudi Fadi N Dahmoush Laila Spector David M Konety Badrinath R |
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Institution: | Department of Urology, University of Iowa, Iowa City, IA 52242-1089, USA. fadi-joudi@uiowa.edu |
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Abstract: | We report on a 38-year-old male diagnosed with biopsy-proven bladder urothelial carcinoma metastatic to the bone, who had a complete response to neoadjuvant chemotherapy consisting of carboplatin and gemcitabine. The final pathology of his radical cystoprostatectomy revealed no residual cancer. The patient continues to be without evidence of disease 2 years postoperatively. This case shows that neoadjuvant chemotherapy with nonstandard regimens can yield responses in patients with bone metastases. |
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