肝脏动静脉渡越时间对原发性肝癌肝脏血流动力学的研究

目的研究肝脏动静脉渡越时间（hepatic arteriovenous transit time，HAVTT）在原发性肝细胞肝癌（hepatic cell carcinoma．HCC）患者中的改变及其对肝脏血流动力学的影响。方法对147例肝脏（非肝硬化HCC组10例,肝硬化HCC组51例。肝硬化组52例，正常对照组34例）行超声造影检查，测量HAVTT。结果正常组与非肝硬化HCC组间HAVTT无明显差异（P〉0．05）。肝硬化HCCHAVTT较非肝硬化HCC组及单纯肝硬化组明显缩短（P〈0．05），且在Child A、C级HCC组间差异显著（P〈0．05）。结论肝硬化合并HCC患者HAVTT明显缩短，Child C级HCC患者的HAVTT明显短于Child A级HCC。

Hepatic Arteriovenous Transit Time Effect on Hepatic Homodynamic Changes in HCC Patients Using Contrast-enhanced Ultrasonography

Objective To study the influence of hepatic arteriovenous transit time(HAVTT) changes on hepa-tic hemodynamics in patients with hepatic cell carcinoma(HCC).Methods One hundred and fourty seven patients including 10 non-cirrhotic HCC,51 cirrhotic HCC,52 cirrhosis patients and 34 healthy adults underwent contrast-enhanced ultrasonography.HAVTT were analyzed after injection of SonoVue into an arm vein. Results There was no significant difference between healthy adults and non-cirrhotic HCC patients(P>0.05).HAVTT was significantly shorter in cirrhostic HCC group than in non-cirrhostic HCC and cirrhosis group(P<0.05),and HAVTT had also significant difference between Child A HCC and Child C HCC group(P<0.05).Conclusions HAVTT was significantly shorter in cirrhosis patients with HCC,especially shorter in Child C than in Child A patients.