纳洛酮、地塞米松治疗慢性阻塞性肺病合并肺性脑病

目的:了解纳洛酮、地塞米松联合治疗慢性阻塞性肺疾病(COPD)合并肺性脑病的疗效。方法:49例入选病例随机分为观察组26例,对照组23例,均给予包括地塞米松在内的常规治疗,观察组在常规治疗的基础上加用纳洛酮。结果:观察组脑功能恢复快,住院时间短,与对照组比较,具显著差异性(P<0.01)清醒后第3d肺通气功能好于对照组(P<0.01)。结论:纳洛酮、地塞米松联合治疗COPD合并肺性脑病,疗效好于常规治疗。

Clinical analysis for chronic obstructive pulmonary disease combined the pulmonary encephalopathy treated with naloxone and dexamethasone

Objective:TO observe the effect for chronic obstructive pulmonary disease combined the pulmonary encephalopathy treated with naloxone and dexamethasone.Methods:49 cases were divided randomly into two groups,the observation group (26 cases) and the control group (23 cases) .Patients in two groups were given the routine treatment include dexamethasone,and the contvol group also given the treatment with naloxone.Results:Brain function of the patients in the observation group was recovered quickly,and pulmonary ventilation test became better than the control group after consciousness 3 days.Therefore,the effect was remarkable comparing with the contro group.Conclusions:Clinical treatment for chronic obstructive pulmonary disease combined the pulmonary encephalopathy treated with naloxone and dexamethasone were better than the routine treatment.