Effect of CYSTUS052® and green tea on subjective symptoms in patients with infection of the upper respiratory tract |
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Authors: | Ulrich Kalus Holger Kiesewetter Hartmut Radtke |
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Institution: | Institute of Transfusion Medicine, Charité‐Universit?tsmedizin Berlin, Berlin, Germany |
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Abstract: | Examples of medicinal herbs that have been perpetuated along several generations based simply on a folk tradition are Cistus and green tea. The principal active constituents of the genus Cistus and green tea are polyphenolic compounds. Polyphenols exhibit a wide range of antibacterial, antifungal and antiinflammatory effects. The present work aimed to investigate the clinical effect of a Cistus extract (CYSTUS052®) in comparison with green tea on 300 patients with infections of the upper respiratory tract. Due to the lack of clinical study data on their efficacy in patients, this is a report of the findings of our study on the clinical efficacy of CYSTUS052® in patients with the upper respiratory tract infections (URTIs). This study observed a total of 300 patients (277 completers) treated with CYSTUS052® given in lozenges compared with treatment with an extract of green tea. The patients scored the subjective severity of target symptoms using a predefined scale. The score of subjective symptoms decreased over the course of treatment with CYSTUS052®, whereas treatment with green tea resulted in a less significant decrease of symptoms. CYSTUS052® therefore proved to be an effective adjuvant for the treatment of respiratory infections. Copyright © 2009 John Wiley & Sons, Ltd. |
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Keywords: | Cistus incanus CYSTUS052® green tea infection of the upper respiratory tract score of subjective symptoms |
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