Haemolytic uraemic syndrome in a patient with acute lymphoblastic leukaemia |
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Authors: | Rachel T. Clarke MBBCh Chris Mitchell PhD |
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Affiliation: | Department of Paediatric Haematology/Oncology, John Radcliffe Hospital, Oxford, UK |
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Abstract: | We describe a patient diagnosed with haemolytic uraemic syndrome (HUS) during long‐term maintenance therapy for childhood acute lymphoblastic leukaemia (ALL). He rapidly developed renal failure, hypertension and profound thrombocytopenia. Despite suffering a large intracerebral haemorrhage, he made a full recovery without residual neurological or renal deficit. His case raises the question of whether ALL or its treatments predispose an individual to developing HUS. Pediatr Blood Cancer. 2010;55:1402–1405. © 2010 Wiley‐Liss, Inc. |
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Keywords: | acute lymphoblastic leukaemia (ALL) haemolytic uraemic syndrome (HUS) thrombotic microangiopathy (TMA) |
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