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Alterations in cholesterol regulation contribute to the production of intratumoral androgens during progression to castration‐resistant prostate cancer in a mouse xenograft model |
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| Authors: | Carlos G. Leon Jennifer A. Locke Hans H. Adomat Susan L. Etinger Alexis L. Twiddy Rachel D. Neumann Colleen C. Nelson Emma S. Guns Kishor M. Wasan |
| Affiliation: | 1. Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, Canada;2. The Prostate Centre at Vancouver General Hospital, University of British Columbia, Vancouver, Canada;3. Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Australia |
| Abstract: | |
| Keywords: | prostate cancer androgens cholesterol metabolism cholesterol synthesis cholesterol cellular influx and efflux castration‐resistance |