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Chemotherapy and interferon‐α treatment of Erdheim–chester disease
Authors:In‐sang Jeon MD  PhD  Sang Seon Lee MD  Min Kyung Lee MD
Institution:1. Department of Pediatrics, Gil Medical Center, Gachon Medical School, Gachon University of Medicine and Science, Incheon, Korea;2. Department of Nuclear Medicine, Gil Medical Center, Gachon Medical School, Gachon University of Medicine and Science, Incheon, Korea
Abstract:Erdheim–Chester disease (ECD) is a rare non‐Langerhans cell histiocytosis of an unknown origin. The prognosis of ECD is variable, and it mainly depends on the involved anatomic sites. The treatment modalities have not been standardized. Interferon‐α (IFN) has been reported to be effective in the management of ECD. We report here on an uncommon case with ECD in a 17‐year‐old female who had multiple lesions in the whole body and she was treated with chemotherapy and IFN. She has remained disease‐free for 2 years after the completion of treatment. Pediatr Blood Cancer. 2010;55:745–747. © 2010 Wiley‐Liss, Inc.
Keywords:Erdheim–  Chester disease  histiocytosis  interferon‐α  
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