Influence of genetic variation in CYP3A4 and ABCB1 on dose decrease or switching during simvastatin and atorvastatin therapy期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

Influence of genetic variation in CYP3A4 and ABCB1 on dose decrease or switching during simvastatin and atorvastatin therapy

Authors:	Matthijs L. Becker PharmD Loes E. Visser PhD PharmD Ron H. N. van Schaik PhD Albert Hofman PhD MD André G. Uitterlinden PhD Bruno H. Ch. Stricker MB PhD

Affiliation:	1. Department of Epidemiology, Erasmus MC, Rotterdam, the Netherlands;2. Hospital Pharmacy, Erasmus MC, Rotterdam, the Netherlands;3. Department of Clinical Chemistry, Erasmus MC, Rotterdam, the Netherlands;4. STAR Medical Diagnostic Center, Rotterdam, the Netherlands;5. Member of the Netherlands Consortium on Healthy Aging, Leiden / Rotterdam, the Netherlands;6. Department of Internal Medicine, Erasmus MC, Rotterdam, the Netherlands;7. Drug Safety Unit, Inspectorate for Health Care, The Hague, the Netherlands

Abstract:

Keywords:	simvastatin atorvastatin pharmacogenetics ABCB1 CYP3A4