| 学龄儿童免疫功能相关影响因素分析 |
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| 引用本文： | 张志红,董洁,郭丽丽,高建伟,乔果果,赵五红. 学龄儿童免疫功能相关影响因素分析[J]. 中国公共卫生, 2010, 26(1) |
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| 作者姓名： | 张志红 董洁 郭丽丽 高建伟 乔果果 赵五红 |
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| 作者单位： | 山西医科大学公共卫生学院环境卫生学教研室,山西太原,030001 |
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| 基金项目： | 国家自然科学基金，山西省青年科研项目 |
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| 摘 要： | 目的了解室内外空气污染对山西省太原市学龄儿童免疫功能的影响。方法选择太原市不同交通污染区11～14岁学龄儿童142名作为研究对象,以问卷形式调查相关因素,用流式细胞仪检测细胞免疫功能(CD3+、CD4+、CD8+、CD4+/CD8+),用免疫比浊法检测体液免疫(IgG、IgA、IgM),用比浊法检测非特异免疫(唾液溶菌酶),用全自动生化分析法检测其他免疫相关细胞(白细胞、淋巴细胞、红细胞、血小板)。结果经多元线性回归分析,细胞免疫功能指标CD3+、CD4+、CD4+/CD8+均与尾气污染程度相关,CD3+还与上学骑自行车或摩托车、冬季采暖使用空调或电暖气因素有关;体液免疫指标IgG主要与冬季采暖方式相关,回归系数为1.172,1.743(P0.05),IgA的影响因素为家居住宅类型,回归系数为-0.301(P0.05);唾液溶菌酶活力的影响因素为尾气污染程度,回归系数为63.945(P0.01);白细胞、淋巴细胞、红细胞、血小板均与尾气污染程度相关,相关系数为-0.513,-0.267,-0.122,-34.855(P0.05)。结论学龄儿童的免疫功能可能与尾气污染程度、上学交通工具、家居住宅类型、冬季采暖方式等因素有关,汽车尾气污染作用突出。
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| 关 键 词： | 学龄儿童 免疫功能 影响因素 交通污染 |
Indoor and outdoor related factors on immune function among school children |
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| ZHANG Zhi-hong,DONG Jie,GUO Li-li,et al.. Indoor and outdoor related factors on immune function among school children[J]. Chinese Journal of Public Health, 2010, 26(1) |
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| Authors: | ZHANG Zhi-hong DONG Jie GUO Li-li et al. |
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| Affiliation: | ZHANG Zhi-hong,DONG Jie,GUO Li-li,et al.Department of Environmental Health,School of Public Health,Shanxi Medical University(Taiyuan 030001,China) |
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| Abstract: | Objective To understand the immune function and the effect of air pollution in school-age children in Taiyuan city of Shanxi province and to provide references for air pollution control.Methods A total of 142 pupils aged 11-14 years in different traffic pollution areas were selected and investigated with a questionnaire.Cell immune functions(CD3+,CD4+,CD8+,CD4+/CD8+) were detected by flow cytometry.Humoral immune functions(IgG,IgA,IgM) were determined with immunological turbidimetry.The acticity of saliva b... |
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| Keywords: | school-age children immune function influence factor traffic pollution |
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