泌尿系感染常见病原菌分布及耐药性分析

目的]了解我院泌尿系感染病原菌的分布及常见病原菌的耐药性，为临床合理用药提供依据。方法]采用API鉴定系统进行病原菌鉴定，用琼脂纸片扩散法（K—B法）进行药敏试验。结果]分离出病原菌282株，其中革兰阴性杆菌199株，占70．57％；革兰阳性球菌67株，占23．76％。检出率最高的是大肠埃希菌，其次为肠球菌和葡萄球菌等。大肠埃希菌对亚胺培南、头孢哌酮／舒巴坦、哌拉西彬他唑巴坦的耐药率较低，分别为1．32％、7．89％、11．18％；肠球菌及葡萄球菌对万古霉素耐药率最低，分别为3．33％和0。结论]泌尿系感染主要由革兰阴性杆菌引起。临床医生应依据药敏试验结果合理使用抗生素。

DISTRIBUTION OF MAIN PATHOGENIC BACTERIA AND ANALYSIS OF DRUG RESISTANCE IN URINARY SYSTEM INFECTION

Objective] To understand the distribution of main Pathogenic bacteria and their drug resistance in urinary system infection in our hospital and provide basis for rational use of drugs. Methods] The bacteria identification system of France biomerieux API was used in the bacterial identification. Drug sensitive test was performed with paper stip method. Results] A total of 282 strains of Pathogenic bacteria were separated from the urine samples of 1068 cases and the number of strains of gram - negative bacilli was 199 ,the gram - positive cocci was 67. The positive rate of Escherichia coli was the highest, which was followed by enterococcus and staphylococci. The drug - resistant rate of E. coli was the lowest to imipenem, which was followed by cefoperazone/sulbactam and piperacillin/tazobactam. The drug - resistant rate of enterococcus and staphylococci was the lowest to vancomycin. Conclusion] The urinary infections are mainly caused by gram - negative bacilli. Physicians must use antibiotics reasonably depending on the results of drug sensitive tests.