“肺鼻同治、祛风化痰”法治疗风热犯鼻证过敏性鼻炎临床疗效观察

目的:通过临床实验研究,观察“肺鼻同治、祛风化痰”法治疗风热犯鼻证过敏性鼻炎的临床疗效,为进一步推广应用奠定临床基础。方法:选取2016年1月至2017年12月中国中医科学院广安门医院南区门诊收治的过敏性鼻炎风热犯鼻证患者76例,脱落剔除病例4例,其余患者采用随机对照的方法分为观察组(n=35)和对照组(n=37),观察组以“麻杏石甘合辛夷汤方”为治疗药物,1剂/d。对照组为西医常规治疗,开瑞坦口服或加曲安奈德鼻喷雾剂,1次/d。治疗周期2周。分别于治疗前、后,进行鼻症状、体征、鼻内镜积分评估。结果:2组治疗后,鼻症状、体征均较前有一定改善,观察组与对照组比较，差异有统计学意义(P<0.01),以观察组为优。临床疗效比较上,治疗后观察组有效率91.43%,优于对照组72.97%,2组比较差异有统计学意义(P<0.05),以观察组疗效最好。随访半年,观察组有效率65.71%,明显优于对照组27.03%。结论:“肺鼻同治、祛风化痰”法能够有效治疗风热犯鼻证过敏性鼻炎,并且在改善症状及临床疗效上可能更加持久和稳定,有较好的临床推广应用价值。

Clinical Efficacy Observation on the Treatment of Allergic Rhinitis Caused by Syndrome of Wind-heat Invading Nose by Treating the Lung and Nose with the Same Treatment,Dispelling Pathogenic Wind and Resoving Phlegm

To observe the clinical efficacy of treating allergic rhinitis with wind heat and nasal syndrome through clinical experiment to lay a clinical foundation for its further application.Methods:A total of 76 patients with allergic rhinitis as syndrome of wind-heat invading nose were selected from January 2016 to October 2017 in the outpatient clinic of South Area of Guang''anmen Hospital,and were divided into 2 groups by randomized controlled method (35 cases in observation group vs 37 cases in control group).The observation group was treated with Maxing Shigan Decoction with Xinyi Decoction 1 dose per day.The control group was treated with conventional western medicine,celitan orally or nasal spray of triamcinolone acetonide once a day.The treatment period was 2 weeks.Nasal symptoms,signs and nasal endoscopy scores were evaluated before and after treatment.Results:After treatment,the nasal symptoms and signs of the two groups were improved to some extent,and the difference between the observation group and the control group was statistically significant (P<0.01),especially in the observation group.Compared with the control group,the effective rate of the observation group was 91.43%,which was better than that of the control group (72.97%).The difference between the two groups was statistically significant (P<0.05),especially in the observation group.The effective rate of the observation group was 65.71%,which was significantly better than that of the control group (27.03%).Conclusion:The method of dispelling pathogenic wind and eliminating phlegm can effectively treat allergic rhinitis caused by syndrome of wind-heat invading nose,and may be more durable and stable in improving symptoms and clinical curative effects.