浮针治疗膝骨关节炎疗效Meta分析

目的:系统评价浮针治疗膝骨关节炎的临床疗效。方法:通过检索CNKI、VIP、万方数据库等中文数据库及三大英文数据库PubMed、Embase、Cochrane,纳入浮针与常规针刺对照治疗膝骨关节炎的随机对照试验,利用Cochrane系统评价方法对纳入文献进行质量评价和资料提取后,采用Review Manager 5.2软件对其进行Meta分析,用漏斗图分析发表性偏倚。结果:共纳入7篇文献,共计595名患者,Meta分析结果显示:与常规针刺比较,浮针或联合其他方式治疗膝骨关节炎的有效率(OR=6.18,95%CI:[3.20,1.92]),疼痛视觉模拟评分VAS改善程度[WMD=-1.22,95%CI(-1.86,-0.58)],差异均有统计学意义(P<0.05),亚组分析结果证实上述结论。结论:浮针能有效治疗膝骨关节炎,但由于纳入研究数量和质量有限,上述结论仍待更多高质量大样本长期随访的研究予以验证。

Meta-analysis of Effectiveness of Fu's Subcutaneous Needling in Treatment of Knee Osteoarthritis

Objective:To systematically evaluate the therapeutic effects of Fu′s subcutaneous needling in treatment of knee osteoarthritis.Methods:By searching Chinese databases such as CNKI,VIP,Wanfang database etc.and 3 major English databases PubMed,Embase,Cochrane,randomized controlled trials of Fu′s subcutaneous needling and conventional acupuncture for knee osteoarthritis were included.After the Cochrane systematic review method was used to evaluate the quality and data extraction of the included literatures,the Meta-analysis was performed by using Review Manager 5.2 software,and the funnel chart was used to analyze the publication bias.Results:A total of 7 literature were included with 595 cases.Meta-analysis results were shown as follows:Compared with conventional acupuncture,the effectiveness of Fu′s subcutaneous needling or combined with other methods for treating knee osteoarthritis(OR=6.18,95%CI:[3.20,1.92]),the degree of improvement in pain visual analogue score VAS[WMD=-1.22,95%CI(-1.86,-0.58)].The differences were statistically significant(P<0.05).The results of the subgroup analysis confirmed the above conclusions.Conclusion:The Fu′s subcutaneous needling can effectively treat knee osteoarthritis.However,due to the limited number and quality of the included studies,the above conclusions are still to be verified by more high-quality large-sample long-term follow-up studies.